Annals of Internal Medicine
Annals of Internal Medicine consistently ranks as one of the world’s most widely read and highly cited peer-reviewed medical journals and earns more than a million page views each month at Annals.org. Annals publishes a wide variety of content in various formats including original research, reviews, guidelines and commentaries relevant to clinical practice, health care delivery, public health, health care policy, medical education, ethics, and research methodology. Articles published in Annals earn significant coverage in the general news media, with more than 21,000 mentions in 2024.
The “Annals: Spotlight on 2024” collection highlighted must-read articles on novel molecular colorectal cancer screening tests, differences in weight gain across several commonly prescribed antidepressants, and health care disparities and solutions that could improve outcomes for underserved communities.
This year, several high-impact articles published in Annals were discussed at Internal Medicine Meeting 2025 during the New in Annals of Internal Medicine: Hear it First from the Authors scientific plenary session.
The articles included:
- Comparison of Initial Artificial Intelligence (AI) and Final Physician Recommendations in AI-Assisted Virtual Urgent Care Visits
- Comparison of Dose Escalation Versus Switching to Tirzepatide Among People With Type 2 Diabetes Inadequately Controlled on Lower Doses of Dulaglutide.
- Cannabis or Cannabinoids for the Management of Chronic Noncancer Pain: Best Practice Advice From the American College of Physicians.
Annals Special Features and Multimedia
Annals of Internal Medicine offers frequently updated multimedia features including videos, graphics and podcasts. Visit https://www.acpjournals.org/journal/aim/multimedia for a full description of each multimedia feature.
This year, Annals launched the Annals Guide to Journal Club. Designed by Annals editors and editorial fellows, this resource helps journal club leaders guide the discussion of core study design and statistical concepts. Each guide features key Annals articles, along with:
- Reading guides — thought-provoking questions to spark discussion.
- Answer keys and slide presentations — clear explanations of study design and statistical methods and how they affect the interpretation of findings.
- Flexible presentation materials — topics from the slide deck that can tailor your Journal Club discussions.
Please note, this is separate from ACP Journal Club, also published by the American College of Physicians.
Annals of Internal Medicine: Clinical Cases
ACP’s and the American Heart Association’s bi-monthly, open access journal Annals of Internal Medicine: Clinical Cases (AIMCC) presents thought-provoking case reports that spark discussion and aid in clinical decision-making. A variety of article types are considered for publication, including case reports, case series, and image and video cases.
Visit https://www.acpjournals.org/journal/aimcc to read published articles, submit a manuscript, or find information on how to become a peer reviewer.
Follow AIMCC on X and Facebook for the latest featured articles.
ACP Clinical Guidelines, Population Health Policies, and Performance Measures
ACP develops clinical guidelines to provide you with recommendations based on the best available evidence, provide guidance when there is no evidence, and help you deliver the best health care possible. ACP has been developing clinical guidelines for nearly half a century and is the oldest clinical guidelines program in the United States.
ACP is internationally recognized for its scientific leadership and rigorous approach to developing trustworthy and transparent evidence-based clinical recommendations. ACP is the only U.S. organization to have earned designations as a GRADE (Grading of Recommendations Assessment, Development and Evaluation) Center and an AGREE (Appraisal of Guidelines for Research and Evaluation) Center and is a founding member of the Cochrane US Network. ACP’s latest advancement was the publication of Incorporating Economic Evidence in Clinical Guidelines: A Framework From the Clinical Guidelines Committee of the American College of Physicians outlining methods for considering economic evidence in the development of clinical recommendations.
This year, ACP published the following papers on important clinical and population health topics:
- Cannabis or Cannabinoids for the Management of Chronic Noncancer Pain
- Pharmacologic Treatments for Acute Episodic Migraine Headache in Outpatient Settings
- Prevention of Episodic Migraine Headache Using Pharmacologic Treatments in Outpatient Settings
- Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults
- Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder
- Outpatient Treatment of Confirmed COVID-19
Visual Clinical Guidelines
- ACP’s Visual Clinical Guidelines, produced in collaboration with Annals of Internal Medicine, provide physicians and other clinicians with a visual summary of clinical guideline recommendations and feature interactive data visualizations.
- Visual Guideline – Prevention of Episodic Migraine Headache Using Pharmacologic Treatments in Outpatient Settings
- Visual Guideline – Pharmacologic Treatments of Acute Episodic Migraine Headache in Outpatient Settings
Performance Measurement
ACP works actively in the field of performance measurement because we recognize its importance in the changing health care environment and want to shape its impact on internal medicine. We understand that physicians question the value of performance measures and that performance measures represent an added burden to an already overworked and under-resourced physician workforce.
ACP conducts a thorough evaluation to review existing performance measures using five criteria: importance, appropriate care, evidence base, specifications, and feasibility/applicability. Based on these reviews, we strategically engage with payers and other important stakeholders in the measurement space to ensure that ACP-supported performance measures are included in value-based programs.
This year, ACP published Quality Indicators for Diabetes in Adults: A Review of Performance Measures by the American College of Physicians and Quality Indicators for Pain in Adults: A Review of Performance Measures by the American College of Physicians, as well as an Ideas and Opinions piece, The Nuances of Performance Measurement and Clinical Guidelines, in Annals of Internal Medicine.
Visit www.acponline.org/guidelines and www.acponline.org/clinical-information/performance-measures to learn more.
DynaMedex®
DynaMed® is collaborating with ACP to provide ACP members free access to DynaMedex®—a powerful point-of-care tool that combines expert clinical content from DynaMed with comprehensive drug information from Micromedex®.
Now featuring Dyna AI, a cutting-edge artificial intelligence search tool, DynaMedex delivers fast, expert-curated, evidence-based answers to natural language queries using content sourced exclusively from DynaMedex, including study summaries, clinical guidelines, and expert commentary to provide guidance you can trust. (Note: Dyna AI can be turned off in your settings if preferred.)
To ensure content accuracy, ACP oversees the peer review of the Overview and Recommendations section of the internal medicine topics most used by ACP members. Look for the ACP logo on these peer-reviewed topics.
Visit https://www.acponline.org/dynamedex to learn more about the benefits of DynaMedex.
More
ACP’s Center for Medical Ethics and Professionalism develops policies and resources on timely issues for ACP members and the public. New ethics papers released this year include:
Optimizing Ethical Care, Quality, and Safety in Long-Term Services and Supports
Ethics and Academic Discourse, Scientific Integrity, Uncertainty, and Disinformation in Medicine
New ACP case studies published this year draw on ethical challenges you may meet in everyday practice, teaching, and research, including:
– “Why Can’t I Be There?” Ethics Regarding Restrictions on Visitation/Family Caregiver Presence
– Responding to Medical Misinformation and Protecting Scientific Discourse and Integrity
– Chaperones, Professional Boundaries and the Potential for Misunderstandings
The ACP Ethics Manual provides a solid foundation for our work on a range of ethical issues and links to position papers and case studies.
Visit our Online Ethics section for more information.
Members are kept well informed about ACP news, clinical updates, and public policy information with ACP’s range of member-exclusive publications, which provide in-depth analysis of issues affecting internal medicine.
I.M. Matters from ACP, ACP’s member newspaper, and its companion e-newsletter, I.M. Matters Weekly from ACP, provide news and information about the practice of medicine and report on the policies, products, and activities of ACP. ACP Hospitalist, a weekly online magazine exclusive to ACP members, covers the latest news in hospital medicine, including feature articles, Q&As, and summaries of recent research. ACP also publishes two monthly clinical e-newsletters, ACP Diabetes Monthly and ACP Gastroenterology Monthly, which summarize recent research about diabetes and gastroenterology/hepatology.
Other ACP e-newsletters include:
ACP Advocate
A bi-weekly newsletter featuring news about public policy issues affecting internal medicine and patient care.
ACP IMpower
A monthly newsletter offering tools, resources, and information to help ACP Resident/Fellow Members during training and prepare them for their professional futures.
IMconnection
A monthly newsletter exclusively for early career physicians that highlights benefits and resources targeted at their career stage.
ACP IMpact
A newsletter for medical students featuring information about internal medicine as a career.
I.M. a Chief Resident
A monthly newsletter offering information and resources for chief residents.
ACP Global
A bi-monthly newsletter offering a global perspective on news in internal medicine and highlighting ACP’s international activities.
ACP JournalWise, a benefit of ACP membership, is a literature surveillance service that is produced in collaboration with McMaster University. Users can set up personalized alerts on topics and specialties of interest from 120 top-tier medical journals, review summaries and follow links to original abstracts, share alerts with colleagues, and browse table of contents from these premier medical journals. Users can access ACP JournalWise anytime from their desktop, tablet, or smartphone.